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Induction of Mutations in Drosophila melanogaster gypsy Retroelements by Modulation of Intracellular Deoxynucleoside Triphosphate Pools In Vivo

The retroviral mutation rate is susceptible to a number of variables, including the balance between intracellular deoxynucleoside triphosphate (dNTP) pools. While this follows from tissue culture studies, the issue has never been addressed directly in vivo. To explore this question in a tractable ex...

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Autores principales: Terzian, Christophe, Henry, Michel, Meyerhans, Andreas, Wain-Hobson, Simon, Vartanian, Jean-Pierre
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2007
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1900171/
https://ncbi.nlm.nih.gov/pubmed/17301142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02558-06
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