Induction of Mutations in Drosophila melanogaster gypsy Retroelements by Modulation of Intracellular Deoxynucleoside Triphosphate Pools In Vivo

The retroviral mutation rate is susceptible to a number of variables, including the balance between intracellular deoxynucleoside triphosphate (dNTP) pools. While this follows from tissue culture studies, the issue has never been addressed directly in vivo. To explore this question in a tractable ex...

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Bibliographic Details
Main Authors: Terzian, Christophe, Henry, Michel, Meyerhans, Andreas, Wain-Hobson, Simon, Vartanian, Jean-Pierre
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2007
Subjects:
Genome Replication and Regulation of Viral Gene Expression
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1900171/
https://ncbi.nlm.nih.gov/pubmed/17301142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02558-06
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