Effect of Preexisting Immunity to Adenovirus Human Serotype 5 Antigens on the Immune Responses of Nonhuman Primates to Vaccine Regimens Based on Human- or Chimpanzee-Derived Adenovirus Vectors

In this study we compared a prime-boost regimen with two serologically distinct replication-defective adenovirus (Ad) vectors derived from chimpanzee serotypes C68 and C1 expressing Gag, Pol, gp140, and Nef of human immunodeficiency virus type 1 with a regimen in which replication-defective Ad vecto...

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Bibliografiska uppgifter
Huvudupphovsmän: McCoy, Kimberly, Tatsis, Nia, Korioth-Schmitz, Birgit, Lasaro, Marcio O., Hensley, Scott E., Lin, Shih-Wen, Li, Yan, Giles-Davis, Wynetta, Cun, Ann, Zhou, Dongming, Xiang, Zhiquan, Letvin, Norman L., Ertl, Hildegund C. J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology (ASM) 2007
Ämnen:
Vaccines and Antiviral Agents
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1900096/
https://ncbi.nlm.nih.gov/pubmed/17428852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02497-06
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