Formation of Hepatitis B Virus Covalently Closed Circular DNA: Removal of Genome-Linked Protein

Hepatitis B virus (HBV) contains a small, partially double-stranded, relaxed circular (RC) DNA genome. RC DNA needs to be converted to covalently closed circular (CCC) DNA, which serves as the template for all viral RNA transcription. As a first step toward understanding how CCC DNA is formed, we an...

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Bibliographic Details
Main Authors: Gao, Weifan, Hu, Jianming
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2007
Subjects:
Genome Replication and Regulation of Viral Gene Expression
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1900077/
https://ncbi.nlm.nih.gov/pubmed/17409153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02721-06
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