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Interdependence of Pes1, Bop1, and WDR12 Controls Nucleolar Localization and Assembly of the PeBoW Complex Required for Maturation of the 60S Ribosomal Subunit

The PeBoW complex is essential for cell proliferation and maturation of the large ribosomal subunit in mammalian cells. Here we examined the role of PeBoW-specific proteins Pes1, Bop1, and WDR12 in complex assembly and stability, nucleolar transport, and preribosome association. Recombinant expressi...

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Detalhes bibliográficos
Main Authors: Rohrmoser, Michaela, Hölzel, Michael, Grimm, Thomas, Malamoussi, Anastassia, Harasim, Thomas, Orban, Mathias, Pfisterer, Iris, Gruber-Eber, Anita, Kremmer, Elisabeth, Eick, Dirk
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1899993/
https://ncbi.nlm.nih.gov/pubmed/17353269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00172-07
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