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Differential Activation of Insulin Receptor Substrates 1 and 2 by Insulin-Like Growth Factor-Activated Insulin Receptors

The insulin-like growth factors (insulin-like growth factor I [IGF-I] and IGF-II) exert important effects on growth, development, and differentiation through the IGF-I receptor (IGF-IR) transmembrane tyrosine kinase. The insulin receptor (IR) is structurally related to the IGF-IR, and at high concen...

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Autors principals: Denley, Adam, Carroll, Julie M., Brierley, Gemma V., Cosgrove, Leah, Wallace, John, Forbes, Briony, Roberts, Charles T.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1899985/
https://ncbi.nlm.nih.gov/pubmed/17325037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01447-06
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