Lanean...

Loss of Gcn5 Acetyltransferase Activity Leads to Neural Tube Closure Defects and Exencephaly in Mouse Embryos

Gcn5 was the first transcription-related histone acetyltransferase (HAT) to be identified. However, the functions of this enzyme in mammalian cells remain poorly defined. Deletion of Gcn5 in mice leads to early embryonic lethality with increased apoptosis in mesodermal lineages. Here we show that de...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Bu, Ping, Evrard, Yvonne A., Lozano, Guillermina, Dent, Sharon Y. R.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2007
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1899977/
https://ncbi.nlm.nih.gov/pubmed/17325035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00066-07
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!