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The p85α Regulatory Subunit of Phosphoinositide 3-Kinase Potentiates c-Jun N-Terminal Kinase-Mediated Insulin Resistance
Insulin resistance is a defining feature of type 2 diabetes and the metabolic syndrome. While the molecular mechanisms of insulin resistance are multiple, recent evidence suggests that attenuation of insulin signaling by c-Jun N-terminal kinase (JNK) may be a central part of the pathobiology of insu...
Kaydedildi:
Asıl Yazarlar: | , , , , , , , , |
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Materyal Türü: | Artigo |
Dil: | Inglês |
Baskı/Yayın Bilgisi: |
American Society for Microbiology
2007
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Konular: | |
Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1899914/ https://ncbi.nlm.nih.gov/pubmed/17283057 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00079-07 |
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