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The p85α Regulatory Subunit of Phosphoinositide 3-Kinase Potentiates c-Jun N-Terminal Kinase-Mediated Insulin Resistance

Insulin resistance is a defining feature of type 2 diabetes and the metabolic syndrome. While the molecular mechanisms of insulin resistance are multiple, recent evidence suggests that attenuation of insulin signaling by c-Jun N-terminal kinase (JNK) may be a central part of the pathobiology of insu...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Taniguchi, Cullen M., Aleman, José O., Ueki, Kohjiro, Luo, Ji, Asano, Tomoichiro, Kaneto, Hideaki, Stephanopoulos, Gregory, Cantley, Lewis C., Kahn, C. Ronald
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2007
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1899914/
https://ncbi.nlm.nih.gov/pubmed/17283057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00079-07
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