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Unusual Interplay of Two Types of Ras Activators, RasGRP and SOS, Establishes Sensitive and Robust Ras Activation in Lymphocytes

Ras activation is crucial for lymphocyte development and effector function. Both T and B lymphocytes contain two types of Ras activators: ubiquitously expressed SOS and specifically expressed Ras guanyl nucleotide-releasing protein (RasGRP). The need for two activators is enigmatic since both are ac...

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Detaylı Bibliyografya
Asıl Yazarlar: Roose, Jeroen P., Mollenauer, Marianne, Ho, Mary, Kurosaki, Tomohiro, Weiss, Arthur
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2007
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1899892/
https://ncbi.nlm.nih.gov/pubmed/17283063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01882-06
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