RAD18 and Poly(ADP-Ribose) Polymerase Independently Suppress the Access of Nonhomologous End Joining to Double-Strand Breaks and Facilitate Homologous Recombination-Mediated Repair

The Saccharomyces cerevisiae RAD18 gene is essential for postreplication repair but is not required for homologous recombination (HR), which is the major double-strand break (DSB) repair pathway in yeast. Accordingly, yeast rad18 mutants are tolerant of camptothecin (CPT), a topoisomerase I inhibito...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Saberi, Alihossein, Hochegger, Helfrid, Szuts, David, Lan, Li, Yasui, Akira, Sale, Julian E., Taniguchi, Yoshihito, Murakawa, Yasuhiro, Zeng, Weihua, Yokomori, Kyoko, Helleday, Thomas, Teraoka, Hirobumi, Arakawa, Hiroshi, Buerstedde, Jean-Marie, Takeda, Shunichi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1899888/
https://ncbi.nlm.nih.gov/pubmed/17242200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01243-06
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados