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A common mechanism for the enhancement of mRNA 3' processing by U3 sequences in two distantly related lentiviruses.

The protein coding regions of all retroviral pre-mRNAs are flanked by a direct repeat of R-U5 sequences. In many retroviruses, the R-U5 repeat contains a complete core poly(A) site-composed of a highly conserved AAUAAA hexamer and a GU-rich downstream element. A mechanism that allows for the bypass...

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Detalhes bibliográficos
Main Authors: Graveley, B R, Gilmartin, G M
Formato: Artigo
Idioma:Inglês
Publicado em: 1996
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC189984/
https://ncbi.nlm.nih.gov/pubmed/8627681
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