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Structural basis of UGUA recognition by the Nudix protein CFI(m)25 and implications for a regulatory role in mRNA 3′ processing

Human Cleavage Factor Im (CFI(m)) is an essential component of the pre-mRNA 3′ processing complex that functions in the regulation of poly(A) site selection through the recognition of UGUA sequences upstream of the poly(A) site. Although the highly conserved 25 kDa subunit (CFI(m)25) of the CFI(m) c...

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Autors principals: Yang, Qin, Gilmartin, Gregory M., Doublié, Sylvie
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2890493/
https://ncbi.nlm.nih.gov/pubmed/20479262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1000848107
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