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The poly(A)-limiting element enhances mRNA accumulation by increasing the efficiency of pre-mRNA 3′ processing

The poly(A)-limiting element (PLE) is a conserved sequence originally found in the 3′ UTR of Xenopus albumin mRNA whose presence restricts the length of the poly(A) tail on both pre-mRNA and fully processed mRNA to <20 nt. Results presented in this study show that the PLE also increases the cytop...

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Detalhes bibliográficos
Main Authors: PENG, JING, MURRAY, ELIZABETH L., SCHOENBERG, DANIEL R.
Formato: Artigo
Idioma:Inglês
Publicado em: Copyright 2005 by RNA Society 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1262677/
https://ncbi.nlm.nih.gov/pubmed/15872182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2020805
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