The role of manganese in promoting multimerization and assembly of human immunodeficiency virus type 1 integrase as a catalytically active complex on immobilized long terminal repeat substrates.

The integration of a DNA copy of the viral genome into the genome of the host cell is an essential step in the replication of all retroviruses. Integration requires two discrete biochemical reactions; specific processing of each viral long terminal repeat terminus or donor substrate, and a DNA stran...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Wolfe, A L, Felock, P J, Hastings, J C, Blau, C U, Hazuda, D J
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1996
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC189962/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8627659/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.70.3.1424-1432.1996
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