Apoptosis is induced by N-myc expression in hepatocytes, a frequent event in hepadnavirus oncogenesis, and is blocked by insulin-like growth factor II.
Induction of hepatocellular carcinoma in woodchucks by woodchuck hepatitis virus is associated with the activation of N-myc gene expression, usually by viral DNA integration in cis to the N-myc locus. We have examined the consequences of N-myc up-regulation in rodent hepatic cells in culture. Mouse...
Na minha lista:
| Publicado no: | J Virol |
|---|---|
| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
1996
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC189956/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8627653/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.70.3.1375-1383.1996 |
| Tags: |
Sem tags, seja o primeiro a adicionar uma tag!
|