Pimet, the Drosophila homolog of HEN1, mediates 2′-O-methylation of Piwi- interacting RNAs at their 3′ ends

Piwi-interacting RNAs (piRNAs) consist of a germline-specific group of small RNAs derived from distinct intergenic loci in the genome. piRNAs function in silencing selfish transposable elements through binding with the PIWI subfamily proteins of Argonautes. Here we show that piRNAs in Drosophila are...

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Bibliografiske detaljer
Main Authors: Saito, Kuniaki, Sakaguchi, Yuriko, Suzuki, Takeo, Suzuki, Tsutomu, Siomi, Haruhiko, Siomi, Mikiko C.
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2007
Fag:
Research Communication
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1899469/
https://ncbi.nlm.nih.gov/pubmed/17606638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1563607
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