Pimet, the Drosophila homolog of HEN1, mediates 2′-O-methylation of Piwi- interacting RNAs at their 3′ ends

Piwi-interacting RNAs (piRNAs) consist of a germline-specific group of small RNAs derived from distinct intergenic loci in the genome. piRNAs function in silencing selfish transposable elements through binding with the PIWI subfamily proteins of Argonautes. Here we show that piRNAs in Drosophila are...

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Detalhes bibliográficos
Main Authors: Saito, Kuniaki, Sakaguchi, Yuriko, Suzuki, Takeo, Suzuki, Tsutomu, Siomi, Haruhiko, Siomi, Mikiko C.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2007
Assuntos:
Research Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1899469/
https://ncbi.nlm.nih.gov/pubmed/17606638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1563607
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