Immune system-dependent and -independent replication of the scrapie agent.

Using the severe combined immunodeficiency (SCID) mouse model, we investigated the requirement of the immune system for the development of scrapie after peripheral inoculation. A total of 33% of SCID mice, all but one immunologically reconstituted SCID mice (93%), and all CB17 control mice developed...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Lasmézas, C I, Cesbron, J Y, Deslys, J P, Demaimay, R, Adjou, K T, Rioux, R, Lemaire, C, Locht, C, Dormont, D
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1996
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC189946/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8551598/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.70.2.1292-1295.1996
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