Vacuolar Leukoencephalopathy with Widespread Astrogliosis in Mice Lacking Transcription Factor Nrf2

NFE2-related factor 2 (Nrf2), an oxidant-activated CNC bZip transcription factor, has been implicated in defense against oxidative stress and chemical insults in a range of cell and tissue types, including the central nervous system. Here, we report that deletion of the Nrf2 gene in mice caused vacu...

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Detalhes bibliográficos
Main Authors: Hubbs, Ann F., Benkovic, Stanley A., Miller, Diane B., O’Callaghan, James P., Battelli, Lori, Schwegler-Berry, Diane, Ma, Qiang
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2007
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1899457/
https://ncbi.nlm.nih.gov/pubmed/17525273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2007.060898
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