Multiorgan Autoimmune Inflammation, Enhanced Lymphoproliferation, and Impaired Homeostasis of Reactive Oxygen Species in Mice Lacking the Antioxidant-Activated Transcription Factor Nrf2

Nuclear factor erythroid 2-related factor 2 (Nrf2) is an antioxidant-activated cap “n” collar basic leucine zipper transcription factor. To assess the function of Nrf2 in the antioxidant response, we examined mice with targeted disruption of the Nrf2 gene. Nrf2-null mice developed complex disease ma...

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Main Authors: Ma, Qiang, Battelli, Lori, Hubbs, Ann F.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Investigative Pathology 2006
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Regular Articles
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1606627/
https://ncbi.nlm.nih.gov/pubmed/16723711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2006.051113
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