Renal Hemodynamic, Inflammatory, and Apoptotic Responses to Lipopolysaccharide in HO-1(−/−) Mice

Lipopolysaccharide (LPS) induces the stress-responsive gene heme oxygenase-1 (HO-1). The present study examined the significance of HO-1 in response to LPS. In HO-1(−/−) mice, as compared with HO-1(+/+) mice, LPS provoked a greater reduction in glomerular filtration rate and renal blood flow, increa...

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Autors principals: Tracz, Michal J., Juncos, Julio P., Grande, Joseph P., Croatt, Anthony J., Ackerman, Allan W., Rajagopalan, Govindarajan, Knutson, Keith L., Badley, Andrew D., Griffin, Matthew D., Alam, Jawed, Nath, Karl A.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2007
Matèries:
Regular Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1899452/
https://ncbi.nlm.nih.gov/pubmed/17525251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2007.061093
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