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Silica Induces Macrophage Cytokines through Phosphatidylcholine-Specific Phospholipase C with Hydrogen Peroxide

Silica particle–associated inflammation is implicated in the genesis of several pulmonary diseases, including silicosis and lung cancer. In this study we investigated the role of phosphatidylcholine-specific phospholipase C (PC-PLC) in silica-stimulated induction of TNF-α and IL-1β and how PC-PLC ac...

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Autors principals: Liu, Honglei, Zhang, Hongqiao, Forman, Henry Jay
Format: Artigo
Idioma:Inglês
Publicat: American Thoracic Society 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1899332/
https://ncbi.nlm.nih.gov/pubmed/17158358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2006-0297OC
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