Prostacyclin Prevents Pulmonary Endothelial Cell Apoptosis Induced by Cigarette Smoke

Rationale: Impaired endothelial cell–dependent vasodilation, inflammation, apoptosis, and proliferation are manifestations of endothelial dysfunction in chronic obstructive pulmonary disease (COPD). Prostacyclin (PGI(2)) is a major product of the cyclooxygenase pathway with potent vasodilatory and a...

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Hlavní autoři: Nana-Sinkam, S. Patrick, Lee, Jong Deog, Sotto-Santiago, Sylk, Stearman, Robert S., Keith, Robert L., Choudhury, Qamrul, Cool, Carlyne, Parr, Jane, Moore, Mark D., Bull, Todd M., Voelkel, Norbert F., Geraci, Mark W.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Thoracic Society 2007
Témata:
B. Chronic Obstructive Pulmonary Disease
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1899287/
https://ncbi.nlm.nih.gov/pubmed/17255567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.200605-724OC
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