CD4-deficient mice have reduced levels of memory cytotoxic T lymphocytes after immunization and show diminished resistance to subsequent virus challenge.
Although primary antiviral CD8+ cytotoxic T lymphocytes (CTL) can be induced in mice depleted of CD4+ T cells, the role of CD4+ T lymphocytes in the generation and maintenance of antiviral memory CTL is uncertain. This question, and the consequences upon vaccine-mediated protection, were investigate...
Guardat en:
| Publicat a: | J Virol |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology (ASM)
1996
|
| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC189913/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8551565/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.70.2.1072-1079.1996 |
| Etiquetes: |
Sense etiquetes, Sigues el primer a etiquetar aquest registre!
|