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Evolutionarily conserved genes preferentially accumulate introns

Introns that interrupt eukaryotic protein-coding sequences are generally thought to be nonfunctional. However, for reasons still poorly understood, positions of many introns are highly conserved in evolution. Previous reconstructions of intron gain and loss events during eukaryotic evolution used a...

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Détails bibliographiques
Auteurs principaux: Carmel, Liran, Rogozin, Igor B., Wolf, Yuri I., Koonin, Eugene V.
Format: Artigo
Langue:Inglês
Publié: Cold Spring Harbor Laboratory Press 2007
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1899115/
https://ncbi.nlm.nih.gov/pubmed/17495009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.5978207
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