Evolutionarily conserved genes preferentially accumulate introns

Introns that interrupt eukaryotic protein-coding sequences are generally thought to be nonfunctional. However, for reasons still poorly understood, positions of many introns are highly conserved in evolution. Previous reconstructions of intron gain and loss events during eukaryotic evolution used a...

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Bibliographic Details
Main Authors: Carmel, Liran, Rogozin, Igor B., Wolf, Yuri I., Koonin, Eugene V.
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2007
Subjects:
Letter
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1899115/
https://ncbi.nlm.nih.gov/pubmed/17495009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.5978207
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