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Evolutionarily conserved genes preferentially accumulate introns

Introns that interrupt eukaryotic protein-coding sequences are generally thought to be nonfunctional. However, for reasons still poorly understood, positions of many introns are highly conserved in evolution. Previous reconstructions of intron gain and loss events during eukaryotic evolution used a...

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Detalhes bibliográficos
Main Authors: Carmel, Liran, Rogozin, Igor B., Wolf, Yuri I., Koonin, Eugene V.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1899115/
https://ncbi.nlm.nih.gov/pubmed/17495009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.5978207
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