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Impaired hippocampal-dependent learning and functional abnormalities in the hippocampus in mice lacking serotonin(1A) receptors

The hippocampus is a major limbic target of the brainstem serotonergic neurons that modulate fear, anxiety, and learning through postsynaptic serotonin(1A) receptors (5-HT(1A) receptors). Because chronic stress selectively down-regulates the 5-HT(1A) receptors in the hippocampus, we hypothesized tha...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Sarnyai, Zoltán, Sibille, Etienne L., Pavlides, Constantine, Fenster, Robert J., McEwen, Bruce S., Tóth, Miklós
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2000
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC18987/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11121072/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.97.26.14731
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