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Norepinephrine-deficient mice lack responses to antidepressant drugs, including selective serotonin reuptake inhibitors
Mice unable to synthesize norepinephrine (NE) and epinephrine due to targeted disruption of the dopamine β-hydroxylase gene, Dbh, were used to critically test roles for NE in mediating acute behavioral changes elicited by different classes of antidepressants. To this end, we used the tail suspension...
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| Główni autorzy: | , , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
National Academy of Sciences
2004
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC419578/ https://ncbi.nlm.nih.gov/pubmed/15148402 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0401080101 |
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