Altered gating of opiate receptor-modulated K(+) channels on amygdala neurons of morphine-dependent rats
The molecular mechanism of tolerance to opiate drugs is poorly understood. We have used single-channel patch–clamp recordings to study opiate receptor effects on dissociated neurons from rat amygdala, a limbic region implicated in addiction processes. A 130-pS inwardly rectifying K(+)-preferring cat...
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| Izdano u: | Proc Natl Acad Sci U S A |
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| Glavni autori: | , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
2000
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC18980/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11121070/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.97.26.14692 |
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