D2 dopamine receptors and the striatopallidal pathway modulate L-DOPA-induced dyskinesia in the mouse

L-DOPA-induced dyskinesia (LID) remains a major complication of Parkinson's disease management for which better therapies are necessary. The contribution of the striatonigral direct pathway to LID is widely acknowledged but whether the striatopallidal pathway is involved remains debated. Selective o...

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Hlavní autoři:	María Sáez, Ettel Keifman, Samuel Alberquilla, Camila Coll, Ramón Reig, Mario Gustavo Murer, Rosario Moratalla
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Elsevier 2023-10-01
Edice:	Neurobiology of Disease
Témata:	L-dopa-induced dyskinesia Parkinson's disease Indirect basal ganglia pathway Optogenetics
On-line přístup:	http://www.sciencedirect.com/science/article/pii/S0969996123002930
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