Induction of susceptibility to tumor necrosis factor by E1A is dependent on binding to either p300 or p105-Rb and induction of DNA synthesis.

The introduction of the adenovirus early region 1A (E1A) gene products into normal cells sensitizes these cells to the cytotoxic effects of tumor necrosis factor (TNF). Previous studies have shown that the region of E1A responsible for susceptibility is CR1, a conserved region within E1A which binds...

ver descrição completa

Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Shisler, J, Duerksen-Hughes, P, Hermiston, T M, Wold, W S, Gooding, L R
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1996
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC189789/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8523594/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.70.1.68-77.1996
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!