Induction of susceptibility to tumor necrosis factor by E1A is dependent on binding to either p300 or p105-Rb and induction of DNA synthesis.

The introduction of the adenovirus early region 1A (E1A) gene products into normal cells sensitizes these cells to the cytotoxic effects of tumor necrosis factor (TNF). Previous studies have shown that the region of E1A responsible for susceptibility is CR1, a conserved region within E1A which binds...

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מידע ביבליוגרפי

הוצא לאור ב:	J Virol
Principais autores:	Shisler, J, Duerksen-Hughes, P, Hermiston, T M, Wold, W S, Gooding, L R
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	American Society for Microbiology (ASM) 1996
נושאים:	Research Article
גישה מקוונת:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC189789/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8523594/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.70.1.68-77.1996
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