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Induction of susceptibility to tumor necrosis factor by E1A is dependent on binding to either p300 or p105-Rb and induction of DNA synthesis.

The introduction of the adenovirus early region 1A (E1A) gene products into normal cells sensitizes these cells to the cytotoxic effects of tumor necrosis factor (TNF). Previous studies have shown that the region of E1A responsible for susceptibility is CR1, a conserved region within E1A which binds...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Virol
Egile Nagusiak: Shisler, J, Duerksen-Hughes, P, Hermiston, T M, Wold, W S, Gooding, L R
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology (ASM) 1996
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC189789/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8523594/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.70.1.68-77.1996
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