Downregulation of Lck-mediated signal transduction by tip of herpesvirus saimiri.

A protein, called tip, of herpesvirus saimiri associates with Lck in transformed T cells. To investigate the effects of complex formation on cellular signal transduction, we constructed human Jurkat-T-cell lines expressing tip. The expression of tip in Jurkat-T cells dramatically suppressed cellular...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Jung, J U, Lang, S M, Jun, T, Roberts, T M, Veillette, A, Desrosiers, R C
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 1995
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC189725/
https://ncbi.nlm.nih.gov/pubmed/7494293
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