Downregulation of Lck-mediated signal transduction by tip of herpesvirus saimiri.
A protein, called tip, of herpesvirus saimiri associates with Lck in transformed T cells. To investigate the effects of complex formation on cellular signal transduction, we constructed human Jurkat-T-cell lines expressing tip. The expression of tip in Jurkat-T cells dramatically suppressed cellular...
Uloženo v:
| Vydáno v: | J Virol |
|---|---|
| Hlavní autoři: | , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Microbiology (ASM)
1995
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC189725/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7494293/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.69.12.7814-7822.1995 |
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