Downregulation of Lck-mediated signal transduction by tip of herpesvirus saimiri.

A protein, called tip, of herpesvirus saimiri associates with Lck in transformed T cells. To investigate the effects of complex formation on cellular signal transduction, we constructed human Jurkat-T-cell lines expressing tip. The expression of tip in Jurkat-T cells dramatically suppressed cellular...

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Publié dans:	J Virol
Auteurs principaux:	Jung, J U, Lang, S M, Jun, T, Roberts, T M, Veillette, A, Desrosiers, R C
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 1995
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC189725/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7494293/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.69.12.7814-7822.1995
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