Mutation of the Lck-Binding Motif of Tip Enhances Lymphoid Cell Activation by Herpesvirus Saimiri

The proline-rich SH3-binding (SH3B) motif of the tyrosine kinase-interacting protein (Tip) of herpesvirus saimiri (HVS) is required for binding to the cellular Src family kinase Lck. We constructed a mutant form of HVS in which prolines in the SH3B motif of Tip were altered to alanines. This mutant...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Duboise, S. Monroe, Lee, Heuiran, Guo, Jie, Choi, Joong-Kook, Czajak, Susan, Simon, Meredith, Desrosiers, Ronald C., Jung, Jae U.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 1998
Soggetti:
Virus-Cell Interactions
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC109695/
https://ncbi.nlm.nih.gov/pubmed/9525577
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi