A point mutation in the VP4 coding sequence of coxsackievirus B4 influences virulence.

In analyzing the molecular determinants of virulence of coxsackievirus B4, chimeric viruses were constructed from avirulent and virulent viruses. The vCB424 recombinant contained a single nucleotide substitution on an avirulent genetic background, resulting in replacement of Ser-16 of VP4 with Arg-1...

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发表在:	J Virol
Principais autores:	Ramsingh, A I, Collins, D N
格式:	Artigo
语言:	Inglês
出版:	American Society for Microbiology (ASM) 1995
主题:	Research Article
在线阅读:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC189653/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7474153/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.69.11.7278-7281.1995
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