A point mutation in the VP4 coding sequence of coxsackievirus B4 influences virulence.

In analyzing the molecular determinants of virulence of coxsackievirus B4, chimeric viruses were constructed from avirulent and virulent viruses. The vCB424 recombinant contained a single nucleotide substitution on an avirulent genetic background, resulting in replacement of Ser-16 of VP4 with Arg-1...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Ramsingh, A I, Collins, D N
Médium: Artigo
Jazyk:Inglês
Vydáno: 1995
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC189653/
https://ncbi.nlm.nih.gov/pubmed/7474153
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky