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Immunization with hepatitis C virus-like particles results in control of hepatitis C virus infection in chimpanzees

Recombinant hepatitis C virus (HCV)-like particles (HCV-LPs) containing HCV structural proteins (core, E1, and E2) produced in insect cells resemble the putative HCV virions and are capable of inducing strong and broad humoral and cellular immune responses in mice and baboons. Here, we present evide...

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Detalhes bibliográficos
Main Authors: Elmowalid, Gamal A., Qiao, Ming, Jeong, Sook-Hyang, Borg, Brian B., Baumert, Thomas F., Sapp, Ronda K., Hu, Zongyi, Murthy, Krishna, Liang, T. Jake
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895966/
https://ncbi.nlm.nih.gov/pubmed/17485666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0702162104
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