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Immunization with hepatitis C virus-like particles protects mice from recombinant hepatitis C virus-vaccinia infection

We have recently demonstrated that immunization with hepatitis C virus-like particles (HCV-LPs) generated in insect cells can elicit both humoral and cellular immune responses in BALB/c mice. Here, we evaluate the immunogenicity of HCV-LPs in HLA2.1 transgenic (AAD) mice in comparison to DNA immuniz...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Murata, Kazumoto, Lechmann, Martin, Qiao, Ming, Gunji, Toshiaki, Alter, Harvey J., Liang, T. Jake
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2003
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC164519/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12748380/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.1131929100
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