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Stabilization of RAD-51–DNA filaments via an interaction domain in Caenorhabditis elegans BRCA2
Mutations in BRCA2 predispose individuals to breast cancer, a consequence of the role of BRCA2 in DNA repair. Human BRCA2 interacts with the recombinase RAD51 via eight BRC repeats. Controversy has existed, however, about whether the BRC interactions are primarily with RAD51 monomers or with the RAD...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1895944/ https://ncbi.nlm.nih.gov/pubmed/17483448 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0702805104 |
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