RAD-51-Dependent and -Independent Roles of a Caenorhabditis elegans BRCA2-Related Protein during DNA Double-Strand Break Repair

The BRCA2 tumor suppressor is implicated in DNA double-strand break (DSB) repair by homologous recombination (HR), where it regulates the RAD51 recombinase. We describe a BRCA2-related protein of Caenorhabditis elegans (CeBRC-2) that interacts directly with RAD-51 via a single BRC motif and that bin...

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Detalhes bibliográficos
Main Authors: Martin, Julie S., Winkelmann, Nicole, Petalcorin, Mark I. R., McIlwraith, Michael J., Boulton, Simon J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Chromosome Structure and Dynamics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1069622/
https://ncbi.nlm.nih.gov/pubmed/15798199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.8.3127-3139.2005
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