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Autoreactive MZ and B-1 B-cell activation by Fas(lpr) is coincident with an increased frequency of apoptotic lymphocytes and a defect in macrophage clearance
Murine autoreactive anti-Smith (Sm) B cells are negatively regulated by anergy and developmental arrest, but are also positively selected into the marginal zone (MZ) and B-1 B-cell populations. Despite positive selection, anti-Sm production occurs only in autoimmune-prone mice. To investigate autore...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
The American Society of Hematology
2006
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1895857/ https://ncbi.nlm.nih.gov/pubmed/16861350 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-12-006858 |
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