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Bradykinin B2 receptor knockout mice are protected from thrombosis by increased nitric oxide and prostacyclin
Bradykinin (BK) liberates nitric oxide, prostacyclin, and tissue plasminogen activator from endothelial cells. We hypothesized that BK B2 receptor knockout (KO) mice (BKB2R(-/-)) have increased thrombosis risk. Paradoxically, the BKB2R(-/-) mice have long bleeding times and delayed carotid artery th...
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| Main Authors: | , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
The American Society of Hematology
2006
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1895832/ https://ncbi.nlm.nih.gov/pubmed/16514058 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-01-0094 |
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