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Analysis of HSC activity and compensatory Hox gene expression profile in Hoxb cluster mutant fetal liver cells
Overexpression of Hoxb4 in bone marrow cells promotes expansion of hematopoietic stem cell (HSC) populations in vivo and in vitro, indicating that this homeoprotein can activate the genetic program that determines self-renewal. However, this function cannot be solely attributed to Hoxb4 because Hoxb...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The American Society of Hematology
2006
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1895826/ https://ncbi.nlm.nih.gov/pubmed/16339407 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-06-2245 |
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