Analysis of HSC activity and compensatory Hox gene expression profile in Hoxb cluster mutant fetal liver cells

Overexpression of Hoxb4 in bone marrow cells promotes expansion of hematopoietic stem cell (HSC) populations in vivo and in vitro, indicating that this homeoprotein can activate the genetic program that determines self-renewal. However, this function cannot be solely attributed to Hoxb4 because Hoxb...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Bijl, Janet, Thompson, Alexander, Ramirez-Solis, Ramiro, Krosl, Jana, Grier, David G., Lawrence, H. Jeffrey, Sauvageau, Guy
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The American Society of Hematology 2006
Gaiak:
Hematopoiesis
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895826/
https://ncbi.nlm.nih.gov/pubmed/16339407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-06-2245
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