AMD3100 mobilizes hematopoietic stem cells with long-term repopulating capacity in nonhuman primates

AMD3100, a bicyclam antagonist of the chemokine receptor CXCR4, has been shown to induce rapid mobilization of CD34(+) hematopoietic cells in mice, dogs, and humans, offering an alternative to G-CSF mobilization of peripheral-blood hematopoietic stem cells. In this study, AMD3100-mobilized CD34(+) c...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Larochelle, André, Krouse, Allen, Metzger, Mark, Orlic, Donald, Donahue, Robert E., Fricker, Simon, Bridger, Gary, Dunbar, Cynthia E., Hematti, Peiman
Format: Artigo
Sprache:Inglês
Veröffentlicht: © 2006 by The American Society of Hematology 2006
Schlagworte:
Transplantation
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895780/
https://ncbi.nlm.nih.gov/pubmed/16439684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-09-3592
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