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Requirement of homotypic NK-cell interactions through 2B4(CD244)/CD48 in the generation of NK effector functions

2B4 belongs to the CD2 subset of the IgG family of receptors. Members in this family have been shown to function as coreceptors via homophilic or heterophilic interactions. Both 2B4 and CD2 bind to CD48, another member of this family. Because all 3 molecules are expressed on natural killer (NK) cell...

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Detalhes bibliográficos
Main Authors: Lee, Kyung-Mi, Forman, John P., McNerney, Megan E., Stepp, Susan, Kuppireddi, Sumalatha, Guzior, Dustin, Latchman, Yvette E., Sayegh, Mohamed H., Yagita, Hideo, Park, Chul-Kyu, Oh, Seog Bae, Wülfing, Christoph, Schatzle, John, Mathew, Porunelloor A., Sharpe, Arlene H., Kumar, Vinay
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society of Hematology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895752/
https://ncbi.nlm.nih.gov/pubmed/15905190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-01-0185
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