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The adapters EAT-2A and -2B are positive regulators of CD244 and CD84 dependent NK cell functions in the C57BL/6 mouse
EAT-2A and EAT-2B are single SH2-domain proteins, which bind to phosphorylated tyrosines of SLAM family receptors in murine NK cells. Whilst EAT-2 is a positive regulator in human cells, a negative regulatory role was attributed to the adapter in NK cells derived from EAT-2A-deficient 129Sv mice. To...
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3255554/ https://ncbi.nlm.nih.gov/pubmed/20962259 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1001974 |
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