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A large upstream region is not necessary for gene expression or hypersensitive site formation at the mouse β-globin locus
Developmental expression at the β-globin locus is regulated in part by the locus control region, a region upstream of the genes containing at least five major DNase I hypersensitive sites (HSs) in mammalian erythrocytes. Sequences farther 5′ of these HSs are conserved in mouse and human, and both lo...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The National Academy of Sciences
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC18957/ https://ncbi.nlm.nih.gov/pubmed/11121056 |
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